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Topics: News, Reviews, Tips, Tutorials, Questions Read more: Adenoviral-mediated co-transfer of TRAIL and interleukin-12 for treating colon cancer. Colorectal cancer is a common malignancy and is a major cause of cancer death worldwide. Therefore, development of novel treatment strategies to control colon cancer is a crucial issue. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and interleukin-12 (IL-12) are potential candidates for cancer therapy. In this study, we co-expressed TRAIL and IL-12 genes in human adenoviral vector and assessed their antitumor effect on colon cancer. An adenoviral vector was constructed encoding TRAIL and IL-12 genes and was used to infect colon cancer cells. Cytotoxicity of TRAIL and IL-12 was evaluated by MTT assay. The effect of combined gene therapy on tumor volume was determined in vivo using a mouse xenograft model. The effect of combination gene therapy on the invasion of colon cancer cells was determined using a transwell chamber. TRAIL and IL-12 genes were expressed in colon cancer cells transfected with adenoviral vector. Combined gene therapy inhibited tumor growth in mouse xenograft model. In addition, adenoviral gene therapy inhibited the invasion of colon cancer cells. The co-expression of TRAIL and IL-12 genes using adenoviral gene therapy was a promising strategy for the treatment of colon cancer.From the Studio: 'Scenic Arts' Spotlight Nearly every American city has at least one artist who is a fixture on the local arts scene, whether they are part of a large-scale performance project, run a program at an arts foundation, or produce a two-dimensional piece or installation at a gallery. There are more than 80 of these artists alone from the New York City area alone. But what of our country's small towns? Scenic Arts and the Emmitsburg Scenic Arts Society have teamed up to spotlight a small-town artist with a large-scale project on tap. This week, Scenic Arts takes a look at 'Scenic Arts' Spotlight artist Laura Reynolds of Emmitsburg, Md. The work of Laura Reynolds, 55, is featured in the new Scenic Arts Art in the Mountains Gallery in Emmitsburg. Reynolds' project is called The Angelica Dollhouse, which she has been working on for the past six months. "It's a dollhouse, a dollhouse of the soul," said Reynolds, who has a background in interior design. "It has a 1a423ce670 PuTTY 1.0.1.0 Crack Download ---------- Allows you to setup the key macros in PuTTY. You need to be sure to have your key file imported into PuTTY and the key file's'set as default' option checked. Key macros can be used to assign key equivalents that control PuTTY's editing of text or scrolling. 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